NETs can be found anywhere in the body where there are neuroendocrine cells. Due in part to the rarity of the disease, NETs are often misdiagnosed and the correct diagnosis usually occurs in the late stages of the illness with approximately 50% of NETs having already spread to other parts of the neuroendocrine system when the diagnosis is made. NETs are considered rare tumors although the incidence of NETs has continued to increase over the course of the last 10-15 years with approximately 12,000 patients being diagnosed in the United States each year. Advances in treatment have improved the length of survival for patients with NETs. Treatment depends on the type of tumor and its location, whether it produces excess hormones, how aggressive it is, and whether it has spread. There are several types of NET, including carcinoid tumors, islet cell tumors, medullary thyroid carcinomas, pheochromocytomas, and neuroendocrine carcinomas of the skin (Merkel cell cancer). Special blood tests can accurately diagnose these tumors. NETs may secrete higher-than-normal amounts of hormones, which can cause conditions including diabetes, flushing, and diarrhea. Because NET symptoms resemble those of other diseases, such as irritable bowel syndrome (IBS) or Crohn’s disease, they are often misdiagnosed. Some tumors grow slowly while others can be very aggressive and spread to other parts of the body (metastasize), most often to the liver or bone. Many NETs start in the digestive tract, as it has more neuroendocrine cells than any other part of the body. NETs are rare and develop most commonly in the lungs, appendix, small intestine, rectum, and pancreas. At follow-up, patient showed partial response (PRRT plus somatostatin analogs). Transaxial 68Ga-DOTANOC PET/CT scans of 62-y-old woman with multiple hepatic secondary NET lesions (gastrinoma). Neuroendocrine cells are located in organs throughout the body and perform specifi c functions, such as regulating air and blood flow and controlling the speed at which food is moved through the gastrointestinal tract. Failure to notify us may result in a radiopharmaceutical recovery fee, not billable to your insurance company.A neuroendocrine tumor (NET) occurs when cells of the body’s neuroendocrine system grow in an uncontrolled, abnormal manner. Neuroendocrine cells have traits similar to nerve cells and to the hormone-producing cells of the endocrine glands. It is preferable for someone to drive you to and from testing.Ĥ8 hours’ notice is REQUIRED if you cancel or reschedule your study. Eat non-carbohydrate items including eggs, bacon, sausage, etc. Do not eat high carbohydrate containing foods for breakfast such as cereal, juice, milk, etc. You may have 12 ounces of water four hours prior to your appointment. If you are scheduled AFTER NOON, you can eat breakfast and take your regular morning dose of diabetic medication with your meal.If you are on oral hypoglycemic medication or insulin, do not take your morning dose until the test is completed. If you are scheduled BEFORE NOON, do not eat after midnight, but you may drink up to 12 ounce of water four hours prior to your appointment time.Limit Milk to 1 or 2 glasses the day before your study.ĭO NOT EAT: Pasta, Potatoes, Rice, Bread, Cereal, Fruits, Sweets, Cakes, Soda (Limit diet soda to 1 or 2), Cough Drops, Cough Medicine, Mints, Gum.ĭO NOT eat for six (6) hours before your test, but you may drink up to 12 ounces of water 4 hours prior to your appointment. YOU MAY HAVE: Green Leafy Vegetables (broccoli, Brussel sprouts, string beans, lettuce, etc), Cheese, Eggs, Meats (pork, beef, veal, chicken, any kind of seafood), Coffee, Tea (limit artificial sweeteners to 1 to 2 servings the day before your study). LIMIT your carbohydrate intake for 24 hours prior to your PET/CT exam. Breast Cancer Screening Recommendations.
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